A new Northwestern Medicine study has uncovered a biological mechanism that may explain why a subset of tumors unexpectedly grows at an accelerated rate after being treated with certain immunotherapies, according to findings published in the journal Cancer Discovery.

A review by University of Manchester scientists says sophisticated lab-grown tumors could help fast-track the search for new cancer treatments while reducing reliance on animal testing.

Molecules called reactive oxygen species, which include so-called “free radicals,” have long been viewed as damaging byproducts of our body’s metabolism—a reason antioxidant supplements have been considered a potential way to reduce cancer risk.

A new biomaterial developed by researchers from The University of Western Australia is providing fresh insights into the way cancer cells escape from tumors and spread through the body.

Where and how does an Alzheimer’s tangle begin? A new study by neuroscientists at Columbia University challenges a long-held assumption about the source of toxic tau proteins, which form neurofibrillary tangles and are closely linked to memory decline in Alzheimer’s disease.

Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically search for new treatment options. They tested more than 1,600 compounds using these organoids and used the results to develop promising drug combinations.

Lab-grown tissues engineered from stem cells reprogrammed from human cells, called human induced pluripotent stem cells (hiPSCs), are rapidly emerging as a more reliable and accessible model in medical research.