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- DISEASE ADVANCES

Deep learning model predicts which heart-failure patients will worsen within a year

Characterized by weakened or damaged heart musculature, heart failure results in the gradual buildup of fluid in a patient’s lungs, legs, feet, and other parts of the body. The condition is chronic and incurable, often leading to arrhythmias or sudden cardiac arrest. For many centuries, bloodletting and leeches were the treatment of choice, famously practiced by barber surgeons in Europe, during a time when physicians rarely operated on patients.

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New cancer therapies target epigenetic switch

Now researchers in the former Laboratory of Chromatin Biology and Epigenetics, headed by C. David Allis until his death in early 2023, have discovered surprising new details about the mechanics of this protein complex, which could potentially lead to new cancer therapies. The findings were published in Genes & Development.

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