MedTech News
.................... by Andrew Celentano

A gel for wounds that won’t heal: Oxygen-delivering technology can prevent amputations
As aging populations and rising diabetes rates drive an increase in chronic wounds, more patients face the risk of amputations. UC Riverside researchers have developed an oxygen-delivering gel capable of healing injuries that might otherwise progress to limb lo

High-performance ECG patch eliminates cold gel and irritating adhesives
Conventional ECG patches often require cold gels and adhesives, which can cause skin irritation and leave marks. These materials can also lose effectiveness during vigorous movement, compromising signal quality. Addressing these issues, UNIST researchers have developed a novel, self-adhesive ECG patch that eliminates the need for gels and chemical adhesives.

Blood and urine DNA tests may help some bladder cancer patients avoid surgery
Researchers at the Icahn School of Medicine at Mount Sinai have reported promising findings that may help redefine treatment for patients with muscle-invasive bladder cancer, a potentially aggressive form of the disease traditionally treated with surgical removal of the bladder. The study, published in the Proceedings of the National Academy of Sciences, demonstrates that ultra-sensitive testing of tumor-derived DNA in blood and urine may help identify patients who can safely preserve their bladder without compromising cancer outcomes.

Urine DNA test may spot Lynch syndrome urinary cancers before symptoms
A pioneering genetic test is improving early diagnosis and treatment for people with hereditary cancer caused by a genetic condition. The test, developed with the help of Newcastle University scientists, identifies specific signs in a person’s DNA that are characteristic of cancers linked with Lynch syndrome.

Oral vaccine strategy used modified bacterium to combat colorectal cancer
A research team investigating the use of the bacterium Listeria monocytogenes against colorectal cancer has discovered a way to build a modified version of Listeria as an oral vaccine to prime the immune system directly within the gut, where anti-tumor cells are then generated. Details of the work, led by Stony Brook immunologist Brian Sheridan, Ph.D., are published in the Journal for the ImmunoTherapy of Cancer.

Eyes may be a window into early Alzheimer’s detection
The eyes—specifically, the outer area of the retina—may provide a window into early detection of Alzheimer’s disease (AD) long before irreversible brain damage has occurred, according to new research from Houston Methodist. This discovery could dramatically change how the disease is diagnosed, monitored and treated.

Can the mental health benefits of exercise be bottled?
We all know the feeling: the mental clarity that comes after a good run or a heavy workout. Science backs this up, even showing that for non-severe depression, exercise can be just as effective as antidepressants or therapy. But there is a cruel irony at play: the symptoms of depression, such as low energy and lack of motivation, are often the very things that can stop people from moving.

Could ‘cyborg’ transplants replace pancreatic tissue damaged by diabetes?
A new electronic implant system can help lab-grown pancreatic cells mature and function properly, potentially providing a basis for novel, cell-based therapies for diabetes. The approach, developed by researchers at the Perelman School of Medicine at the University of Pennsylvania and the School of Engineering and Applied Sciences at Harvard University, incorporates an ultrathin mesh of conductive wires into growing pancreatic tissue, according to a study published in Science.