MedTech News
.................... by Andrew Celentano
Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation
The first-in-human clinical phase I trial assessing the feasibility and safety of WDVAX, an immunostimulatory biomaterial-based cancer vaccine, in a cohort of 21 patients with stage 4 metastatic melanoma, was concluded with positive outcomes that encourage future vaccine developments and trials to test them in combination with immune checkpoint inhibitor therapies.
AI-engineered nasal spray antiviral platform developed to block flu and COVID-19
Respiratory viruses that have diverse strains and mutate rapidly, such as influenza and COVID-19, are difficult to block perfectly with vaccines alone. To solve this problem, KAIST’s research team has successfully developed an intranasal antiviral platform using AI technology to overcome the existing limitations of interferon-lambda treatments—namely, being weak against heat and disappearing quickly from the nasal mucosa.
New AI tool identifies not just genetic mutations, but the diseases they may cause
Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only identifies disease-causing genetic mutations but also predicts the type of disease those mutations may trigger.
Gut bacteria from amphibians and reptiles achieve complete tumor elimination in preclinical model
A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity
AZmed Expands Into CT Imaging With CE-Marked AZnod, An AI Tool for Lung Nodule Detection and the First Product in the Rayscan® Line
PARIS, Dec. 15, 2025 /PRNewswire/ — AZmed, one of the leading companies in artificial intelligence (AI) for radiology, announced today the CE marking of AZnod, its first AI tool for computed tomography (CT) within the new Rayscan® product line. This expansion complements AZmed’s existing Rayvolve® AI Suite, extending the company’s portfolio beyond standard X-rays to include advanced CT-based analysis.
Vaxxas gains Australia’s TGA licence to manufacture HD microarray patch
The patch is tailored to deliver all types of vaccines to the skin using a simple applicator.
Continuous dialysis implant wins FDA Breakthrough Device Designation
The FDA has granted Breakthrough Device Designation to Nephrodite’s Holly implantable continuous dialysis system.
Scientists develop mini human heart organoid that mimics atrial fibrillation
Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular and often fast heartbeat, it’s been at least 30 years since any new treatments have been developed. This is because researchers haven’t had accurate models of the human heart to study. Thanks to new developments from Michigan State University scientists, that is no longer the case.