MedTech News
.................... by Andrew Celentano

Simple mouth rinse may help detect stomach and colorectal cancer signals
It’s widely understood that the microbiome—especially microbes found in the mouth and the gut—can have a profound effect on health. In a study published in the journal Cell Host & Microbe on Aug. 20, researchers report that by analyzing the makeup of oral microbes, they may be able to detect signals associated with gastric (stomach) and colorectal cancer. These findings could lead to the development of new, less invasive screening tests for gastrointestinal cancers.

Microglia caught eating living motor neurons in ALS mice via unexpected immune pathway
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that, according to the CDC, currently affects around 35,000 Americans—with 5,000 more diagnosed each year. Risk climbs with age, and treatments only slow progression. With no cure and an aging population, scientists are urgently seeking insights that could change those devastating outcomes.

Maverix Medical Announces FDA 510(k) Clearance for the Narwhal™ Cryo System
Console-free, single-use cryoprobe brings cryobiopsy to the bronchoscopy suite without dedicated capital equipment

Hematogenix’s MM MRD Assay Underpins FDA Accelerated Approval of Bristol Myers Squibb’s ZENBEXUS™, the First Approved CELMoD Therapy for Multiple Myeloma
Hematogenix’s proprietary Multiple Myeloma MRD (MM MRD) assay measured the primary efficacy endpoint cited in the FDA-approval of ZENBEXUS (iberdomide), reinforcing Hematogenix’s role as a specialized global leader in registrational oncology trials.

Turning brain neurons on and off with light: A reversible synaptic switch
A research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, DGIST, in collaboration with a team led by Professor Alice Ting at Stanford University, has developed LATeNT, a novel optical control platform that uses light to block signal transmission between neurons and subsequently restore normal signaling. The work is published in the journal Nature Methods.

Single gene injection reverses inherited heart disease in mice and patient-grown tissue
Melbourne researchers have made a gene therapy breakthrough that could restore heart function in children with genetic heart disease, sparing them the need for transplants.

New norovirus vaccine approach may shape strategies for treating other RNA viruses as well
Every RNA virus—from stomach bugs and influenza to measles and the common cold—has its own story to tell, with a unique combination of symptoms, transmission rates, duration and chemical blueprint.

Ambient light activates wearable patch for wound treatment
A research team has developed a wearable patch that simultaneously promotes wound closure and tissue regeneration using room light or sunlight, without batteries or an external electrical power source. The work has been published online in Advanced Materials.