MedTech News
.................... by Andrew Celentano
Experimental chemotherapy uses stealth tactic to activate inside cancer cells
Chemotherapy faces a fundamental problem: The same drugs powerful enough to kill cancer cells can also damage healthy tissue.
Novel CAR-T therapy shows promising safety and durable responses in hard-to-treat multiple myeloma
Patients with relapsed or refractory multiple myeloma often run out of effective treatment options after multiple rounds of therapy.
How the APOE4 gene damages brain blood vessels in Alzheimer’s disease
Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer’s disease, damages the brain’s blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.
Eli Lilly’s weekly insulin shot cleared by FDA, setting up another front in Novo rivalry
The weekly insulin Onswik will now be available to U.S. patients after initial approvals in Europe, Mexico and Japan.
Biologists identify a cellular pathway that allows colorectal cancer to metastasize
They also found that obesity may put patients at higher risk for activation of the pathway. Drugs that block the pathway may help prevent metastasis.
FDA panel endorses GRAIL’s multi-cancer early detection test
The panel voted 7-2 vote in favour of GRAIL’S Galleri multi-cancer early detection (MCED) test’s benefits outweighing its risks.
Researchers identify cellular stress-protection system that may help tumors withstand chemotherapy
Many cancer treatments work by exploiting weaknesses in tumor cells, overwhelming their ability to survive, repair damage or continue growing. Yet some cancer cells manage to survive treatment. A new study from Texas A&M University sheds light on one reason why: Some cancer cells have a survival toolkit.
Drug combination study reveals new clues to treatment resistance in deadly melanoma
Uveal melanoma is a rare, aggressive cancer that starts inside the eye and often spreads to the liver. Few treatment options exist, and unlike some forms of skin melanoma that can respond well to modern therapies, metastatic uveal melanoma (MUM) remains difficult to treat.