MedTech News

.................... by Andrew Celentano

Shape-shifting drug hits tumors in multiple ways, improves outcomes in mice

Modern anticancer medications that combine tumor-fighting drugs with proteins that specifically target cancer cells are a relatively new class of drugs, often given to patients for whom standard chemotherapy has not worked. The drugs are precise but can attack only one type of target in a cancer cell at a time. This limits their effectiveness against tumors containing multiple types of targets, which becomes more likely as cancer progresses or tumors become resistant to conventional therapies.

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New machine-learning equation accurately assess LDL cholesterol risk

The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk. Now, a simplified machine-learning version of this equation has been shown in a study of millions of U.S. adult and child blood samples to match the accuracy of the original—making it broadly accessible.

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