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- DISEASE ADVANCES

Osteoporosis fractures fall by 94% in small first-in-human stem cell trial

Somewhere in the world, a woman over 50 will have fractured a bone by the time you finish reading this sentence due to osteoporosis, a silent bone disease that can weaken the structural integrity of the skeletal system and a person’s quality of life. The disease weakens bones and makes them more likely to break because of reduced bone mineral density and bone mass, and it affects an estimated 75 million people across Europe, the USA, and Japan.

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New ablation approach improves outcomes for persistent atrial fibrillation

Atrial fibrillation is the most common cardiac arrhythmia and increases the risk of conditions such as stroke and heart failure. An established treatment is catheter ablation, in which physicians use thin catheters to create small scars in heart tissue to block the electrical signals that cause the arrhythmia. Despite treatment, many patients with the more difficult-to-treat form, persistent atrial fibrillation, experience recurrence.

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Magnetic pulses reprogram immune cells to fight breast cancer in preclinical models

Researchers from the National University of Singapore (NUS) have demonstrated an innovative approach for targeted breast cancer therapy using pulsed electromagnetic fields (PEMFs). The NUS team successfully reprogrammed tumor-associated macrophages (TAMs), a corrupted class of immune cells that typically promote cancer growth, into an active anti-tumor state that attacks and destroys cancer cells.

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