Researchers at the University of Massachusetts Amherst have designed non-toxic Salmonella bacteria to deliver viruses that are safe to humans but potent against liver and pancreatic cancer tumors—two cancers with an extremely poor prognosis.
Researchers at McMaster University have discovered a new antibiotic that kills some of the world’s most dangerous and drug-resistant bacteria—and does so by targeting a previously unknown vulnerability, opening the door to an entirely new class of treatments.
A Yale study published in the journal Bioactive Materials found that the medication lacosamide acts as a highly effective, dual-purpose treatment that relieves joint pain and reverses cartilage damage in osteoarthritis, especially when a specialized hydrogel delivers the drug directly into the joint.
The adjuvant can help the injectable polio vaccine induce a strong immune response in the GI tract, which is considered critical to eradicating the virus.
The result is NeuroSense, a monitoring system that connects to drainage lines to detect biomarkers of infection, including changes in glucose, lactate and pH, as well as flow rate, as brain fluid moves through them.
Researchers used an open-source AI model called Mirai, which was developed by the study’s senior author, UC Berkeley data scientist Adam Yala, Ph.D.
Di Wang, Ph.D., and Y. Shrike Zhang, Ph.D., of the Division of Engineering in the Mass General Brigham Department of Medicine, the lead and senior authors of the study published in Nature Biomedical Engineering, developed a special gel-like material whose expansion speed and final size can be carefully controlled. The paper is titled “4D-printed adaptive hydrogel tissue expanders for ear and breast reconstruction.”
MIT engineers have developed a noninvasive pacemaker that stimulates the heart using ultrasound. The design could one day provide a surgery-free alternative to traditional cardiac implants.
Researchers from the Icahn School of Medicine at Mount Sinai have uncovered the first direct evidence that deep brain stimulation (DBS) can remodel white matter pathways in the brain and alter communication across large-scale neural networks, revealing a previously unrecognized mechanism that may explain how the therapy helps patients recover from severe depression.
Developed by an international team, led by scientists at UCL and at the Allen Institute (Seattle, US), the research forms part of a project investigating Neuropixels probe technology.