MedTech News
.................... by Andrew Celentano

Targeted antibody treatment reverses diabetic nerve damage in mouse models
A team of UTHealth Houston researchers slowed and even reversed diabetic nerve damage in mice, bringing researchers one step closer to developing a treatment for humans. The research is published in Science Translational Medicine.

Highly potent compound that blocks Ebola virus entry discovered
A University of Minnesota–led multi-institutional research team has discovered a highly potent small molecule that blocks Ebola virus entry by stabilizing the virus’s entry protein and provides strong protection when given orally in a preclinical model.

Nasal spray protects neurons and memory in Alzheimer’s mouse model
A nasal spray containing vesicles naturally released by cells may work against Alzheimer’s. This is the promise of a study conducted by researchers at the Università Cattolica, Fondazione Policlinico Universitario A. Gemelli IRCCS, and the E. Menni Research Center of Fondazione Poliambulanza.

New imaging combines light and sound to watch brain oxygen supply in real time
The brain is a black box of densely packed neurons, blood vessels and immune cells, all locked away in a sealed skull. WashU’s Song Hu has dedicated his career to unlocking that puzzle box by developing new ways to “see” inside. His team’s newest innovation could give researchers a new view of how brain cells and blood vessels work together and what happens when the coupling between the two breaks down.

Protein-based MRI agent detects lung cancer and hidden metastases earlier than current scans
A multi-institutional research team led by Georgia State University Regents’ Professor Emerita of Biochemistry and Biophysical Chemistry Jenny J. Yang has developed a new class of protein-based MRI contrast agents that detect invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.

Not all colonoscopies are the same. New AI tool audits them at scale.
Study of 19,000 colonoscopies shows AI can accurately assess quality metrics from procedure videos

Abbott earns FDA approval for new dual-energy ablation catheter
Abbott (NYSE: ABT) earned FDA approval for its new dual-energy catheter, TactiFlex Duo sensor-enabled ablation catheter.

Vitamin A metabolite keeps immune cells active against recurrent brain tumors
Immune cells can become exhausted after prolonged exposure to cancer, gradually losing their ability to attack tumor cells. This phenomenon is particularly pronounced in aggressive brain tumors and can severely limit the effectiveness of immunotherapy.