Engineers and neuroscientists at the University of California San Diego have developed a soft, wearable fingertip patch that continuously tracks a patient’s Parkinson’s disease medication levels through sweat. The device operates using chemicals in the patient’s sweat—no batteries required. Its measurements were comparable to those obtained by standard laboratory blood tests.
Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a “cold” tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.
Every year, untreated tooth decay sends thousands of young U.S. children to emergency departments for dental problems doctors can’t treat. Many eventually undergo surgery under general anesthesia, while others endure pain and infection.
Every encounter between a T cell and a potential target—especially when that target is a developing tumor—begins with a rapid series of molecular decisions. Within seconds, the immune cell must determine whether to launch an attack or stand down. T cells are so potent, so potentially devastating, that misreading the situation can cause serious tissue injury.
The international research team found that resistant cancer cells can hijack a specific DNA repair defence mechanism to protect themselves from the effects of PARP inhibitors
Engineers at the University of California San Diego created a smart ring that simultaneously and continuously monitors up to four different chemical biomarkers from finger sweat. The biomarkers the smart ring can monitor in sweat are glucose, ketones, vitamin C, uric acid, lactate and alcohol.
Northwestern scientists have developed a novel wireless sensor device that can continuously monitor skin elasticity in patients with soft tissue disorders, including lymphedema and scleroderma, which can support early disease detection and better inform care strategies, as detailed in a study published in Science Advances.
Researchers in Korea have developed a new near-infrared (NIR) fluorescent dye with significantly improved photostability, overcoming the rapid signal fading that has long limited fluorescence imaging during surgery for cancer, lymph node mapping and other medical procedures.
Biomedical engineers at Duke University have developed an injectable biomaterial that helps transform the cavity left behind after a stroke caused by a blood clot into an environment more supportive of repair. By recruiting the body’s own immune cells, the treatment promoted the growth of new blood vessels, supported neural remodeling and improved motor performance in mice. The work appears in Cell Biomaterials.
Here are some of the latest cancer breakthroughs in research, testing, and treatment.