
How ‘good’ bacteria from fecal transplants reduce peanut allergy
Some 33 million Americans have severe food allergies. Now, researchers at Boston Children’s Hospital may have found a promising solution.

Some 33 million Americans have severe food allergies. Now, researchers at Boston Children’s Hospital may have found a promising solution.

Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the “undruggable” PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic cancer, grow and resist treatment. In laboratory studies, the drug slowed tumor growth, improved survival and enhanced the effects of the chemotherapy drug gemcitabine.

Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts cancer cells’ ability to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 to treat human cancer in the future.

Six years after the height of the COVID-19 pandemic, scientists are still uncovering surprising ways the virus can wreak havoc on the body. A new UCLA study published in Science Advances describes a previously unrecognized way the SARS-CoV-2 nucleocapsid protein—a structural protein less familiar than the spike protein that has dominated public attention and much vaccine research—can push the immune system into dangerous overdrive.

Spinal cord injuries affect an estimated 15 to 20 million people worldwide, often causing lasting impairments in movement, sensation and independence. Such injuries can be especially devastating when they occur at the level of the neck, where damaged spinal circuits disrupt signals that control the diaphragm, the main muscle used for breathing.

Viral reservoirs in a proxy animal model of HIV share features with immune-suppressive tumors

Many medical devices and wearable health sensors work by shining light into the skin and measuring the signal that returns. These technologies are used in products ranging from pulse oximeters to fitness trackers. However, studies have shown that some optical devices can be less accurate for people with darker skin, raising concerns about health care equity and patient safety. In a recent study reported in the Journal of Biomedical Optics, researchers at the VTT Technical Research Centre of Finland addressed this problem by developing realistic skin-like test models that represent a range of skin tones and include artificial blood vessels with flowing blood-like fluid.

Radiopharmaceutical therapy (RPT) has made significant strides over the past 50 years, although it only recently received FDA approval to treat prostate cancer.

Congenital heart disease affects approximately two in every 100 newborns globally. But why does it occur? An important part of the answer may lie in a previously unknown mechanism on the surface of our cells. Researchers from the University of Copenhagen identified this mechanism in a new study.

Tiny, near-invisible fragments of plastic shed from the products we use every day through sunlight and mechanical wear have been quietly working their way deep into the human body. Microplastics have already been found in the human brain, semen and even the placenta. A recent study investigated how these micro- and nanoplastics (MNPs) might move through the placenta and whether they affect a baby’s development.