MedTech News
.................... by Andrew Celentano

How melanoma silences the skin’s natural antitumor defense
Researchers from the Atopy (Allergy) Research Center of the Juntendo University Graduate School of Medicine in Japan, led by Prof. François Niyonsaba, along with co-authors Quan Sun and Ge Peng, explored the relationship between melanoma cells and keratinocytes, the most abundant cells in the skin that surround melanoma cells.

Smart walker boosts walking efficiency and dynamic balance in older adults
Researchers have evaluated a novel smart wheeled walker designed to enhance mobility and safety for aging populations. Published in JMIR Aging, the randomized crossover trial revealed that the smart wheeled walker significantly improved walking speed, reduced exertion and boosted dynamic balance compared with a traditional 4-wheeled rollator.

Supplement plus chemotherapy boosts pancreatic cancer survival
When added to standard chemotherapy, a clinical version of the dietary supplement L-glutamine improved survival in an early-phase trial of patients with advanced pancreatic cancer. The study, led by Cedars-Sinai Health Sciences University investigators, was published in Nature Cancer.

Lab-grown nerves match human sensory signal speeds, enabling tests of myelin repair
Rice University and collaborators in Switzerland have developed a platform to grow human-derived nerve cells and Schwann cells, supporting cells that form a protective coating called myelin around nerve fibers.

Hidden immune cells in the lung could lead to better flu vaccines
Most current flu vaccines—especially those given by injection—do not reliably build strong immune memory in the airways, leaving a gap in protection against initial infection and transmission.

Cancer’s malignant remote control: How tumors reprogram liver fat metabolism to disarm immune cells
In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century explored the genetic aberrations and microenvironmental peculiarities of tumors and their constituent cells.

A ‘one-two punch’ against aggressive breast cancer could offer an alternative to chemotherapy
Triple-negative breast cancer (TNBC) has a frustrating ability to adapt. Although this aggressive form of breast cancer can initially respond well to chemotherapy, cancer cells often find ways to survive, allowing the disease to return and become resistant to treatment.

Stress proteins actively sustain joint inflammation in osteoarthritis, study finds
Why do some joints remain chronically inflamed in osteoarthritis and other rheumatic diseases?