MedTech News
.................... by Andrew Celentano
The First 3D Map of an Ovary Suggests a Hidden System Controls Egg Activation
Researchers have developed a 3D map of an ovary for the first time, enabling a deeper understanding of how and when oocytes — immature eggs — are activated. Published in the journal Nature Aging, the team believes their findings have important implications for human reproductive health, as well as opening the door to future studies.
Ultragenyx wins FDA greenlight for first Sanfilippo therapy, priced at nearly $4M
The FDA has given the go-ahead to Ultragenyx’s rebisufligene etisparvovec—now to be marketed under the brand name Fayuvi—for the treatment of Sanfilippo syndrome type A, an ulta-rare, progressive neurological condition in children.
Ferronova reports early MAGMAP results for nanoparticle-guided cancer lymph node mapping
The 62-patient multicentre trial is evaluating a nanoparticle-based platform designed to help identify sentinel lymph nodes in gastric and oesophageal cancer surgery.
A gut’s complex architecture, recreated on a microscope slide–sized chip
Gut instinct, gut feeling or gutting it out—what exactly is the human gut? It’s the workhorse of the digestive system and home to a vast, dynamic community of microorganisms that influence human health. In fact, the human body contains roughly equal numbers of nonhuman (microbial) and human cells.
Teaching the immune system to control HIV
There is no cure for HIV. While scientists have made considerable progress in controlling the infection, patients still must take daily antiretroviral medication for the rest of their lives. Results from a clinical trial led by Rockefeller, Imperial College London, and the University of Oxford (RIO) have offered a new strategy, suggesting that just one or two doses of broadly neutralizing antibodies (bNAbs) can suppress the virus long term, keeping it at undetectable levels for months and even years.
Forgotten and Overlooked Structure Attached to the Ovary May Be Far More Active Than Once Thought
The rete ovarii (RO) is a small structure attached directly to the ovary that has largely faded from view since it was first described more than a century ago. Its name comes from the Latin word for “network,” referring to the interconnected tubes and channels that make up the structure, according to the National Cancer Institute.
Women experience less pain during IUD insertion using a new method
A simple method involving local anesthesia in the uterus can reduce pain during IUD insertion, according to a new study from Karolinska Institutet, published in the journal JAMA. The method also increased the proportion of women who found the procedure tolerable. The results may encourage more women to choose an IUD as a contraceptive method.
Continuous glucose monitors may reveal hidden heart risk patterns in adults without diabetes
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are the clinical gold standards for screening blood sugar levels, yet they provide only static snapshots that fail to reflect the highly dynamic and heterogeneous nature of metabolic impairment. However, continuous glucose monitoring (CGM) is reshaping our understanding of these levels. While the medical community already has begun capitalizing on CGM for diabetes management, a new study has the potential to change current clinical practices for cardiovascular disease risk stratification in individuals without diabetes.