MedTech News
.................... by Andrew Celentano

BlueWind Medical earns FDA clearance for next-gen tibial neuromod system
BlueWind Medical announced today that it received FDA 510(k) clearance for Revi Extend, its next-generation implant.

New biobank of tumor models reveals cancers’ weak spots
A new open resource of cancer models has enabled researchers to create the first large-scale map of the genes that cancers rely on to survive, offering new avenues for research into better and less toxic treatments for patients.

RNA technology improves insulin-producing cell transplantation outcomes
Researchers from the Rolf Luft Research Center for Diabetes and Endocrinology at Karolinska Institutet have developed a targeted RNA technology to prepare pancreatic islet cells for transplantation.

How ‘good’ bacteria from fecal transplants reduce peanut allergy
Some 33 million Americans have severe food allergies. Now, researchers at Boston Children’s Hospital may have found a promising solution.

First-in-class small molecule inhibitor shows promise against pancreatic cancer in preclinical studies
Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the “undruggable” PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic cancer, grow and resist treatment. In laboratory studies, the drug slowed tumor growth, improved survival and enhanced the effects of the chemotherapy drug gemcitabine.

A new drug that can potentially overcome cancer therapy resistance
Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts cancer cells’ ability to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 to treat human cancer in the future.

A lesser-known SARS-CoV-2 protein may offer clues to long COVID symptoms
Six years after the height of the COVID-19 pandemic, scientists are still uncovering surprising ways the virus can wreak havoc on the body. A new UCLA study published in Science Advances describes a previously unrecognized way the SARS-CoV-2 nucleocapsid protein—a structural protein less familiar than the spike protein that has dominated public attention and much vaccine research—can push the immune system into dangerous overdrive.

Engineered human neurons rebuild damaged spinal cord circuits
Spinal cord injuries affect an estimated 15 to 20 million people worldwide, often causing lasting impairments in movement, sensation and independence. Such injuries can be especially devastating when they occur at the level of the neck, where damaged spinal circuits disrupt signals that control the diaphragm, the main muscle used for breathing.